Caudal Regression Syndrome/neurogenic bladder presented as recurrent urinary tract infection

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Burhan Edrees


Caudal Regression Syndrome (CRS) is also known as ‘Sacral Agenesis’
which represents vertebral anomaly and imperfections in the
caudal region. It is a congenital syndrome; therefore, abnormalities
in the fetal development are serious outcomes of this condition.
Impaired development in the caudal region will affect the general
health status of the patients.1 This syndrome usually occurs in
combination with morphologic dysfunction of the feet and spinal
cord malformations. It can be said that CRS is a rare and serious
medical condition, which should be addressed properly.2 Vertebral
column bone malformations, bones of feet and legs, the pelvic
bone, absent genitalia, blocked opening of the anus, and ureters
fused are some of the symptoms of CRS.1
Urinary tract infection is a very common medical condition,
which mostly occurs in hospitals or clinical settings ‘nosocomial
infection’.3 Difficulty in urination and impaired functioning of the
bladder are two extremely common symptoms of urinary tract
infection. A proper treatment approach is required by the professionals
to eliminate the condition of UTI (Urinary Tract Infection)
Neurogenic bladder is another very common condition, in
which an individual lacks the control of bladder because of deformities
within the spinal cord, brain, or nervous supply. A number
of nerves and muscles mostly work together for the attainment
of specified function. A very common example regarding the bladder
is, urinary incontenince. In this condition, the brain is unable to
control the functions of bladder, which results in neurogenic bladder.
5 These three medical conditions have similar signs, symptoms,
and nature, which frequently result in poor diagnosis.

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Author Biography

Burhan Edrees

Department of Pediatrics, Medical College, Umm Al-Qura University, Saudi Arabia